GABAB Receptors, Schizophrenia and Sleep Dysfunction: A Review of the Relationship and its Potential Clinical and Therapeutic Implications

Evidence for an intrinsic relationship between sleep, cognition and the symptomatic manifestations of schizophrenia is accumulating. This review presents evidence for the possible utility of GABAB receptor agonists for the treatment of subjective and objective sleep abnormalities related to schizophrenia.