Synthesis and Characterization of Doped Bioactive Glasses

Abstract Bioactive glasses have been studied for several years. Hench has been the first to show their interest as bone substitutes. Bioglass 45S5 is the best known. This work reviews bioactive glasses of the SiO 2 , CaO, and Na 2 O domain. P, F, and N dopings are also presented. Mixture designs have been used to synthesize the best bioactive glass and to limit the essays. Structures have been studied by NMR analyses. Mechanic properties have been studied as a function of N ratios. Bioactivity has been determined by Fourier Transform Infrared (FTIR) spectroscopy in terms of time of HCA layer’s nucleation. The layer’s thickness has been estimated by Scanning Electron Microscopy coupled with Energy Dispersion Spectroscopy (SEM-EDS) analyses. The last part is about sol-gel synthesis and the Ag doping of an invert glass with 47% SiO 2 , 26.5% CaO, 21.5% Na 2 O, and 5% P 2 O 5 composition.