Novel acid-free cleavage of N-(2-hydroxyarylidene) protected amines
2001
Abstract A novel, mild, neutral and selective procedure for deprotection of salicylaldehyde protected primary amines has been developed. Examples in nucleoside, polyamine and amino acid chemistry are given in which N -salicylidene derivatives were selectively deprotected with methoxyamine in the presence of other typical protecting groups for these compounds.
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