Use of Highly Active Antiretroviral Therapy Is Associated With Lower Prevalence of Anal Intraepithelial Neoplastic Lesions and Lower Prevalence of Human Papillomavirus in HIV-Infected Men Who Have Sex With Men

cious for AIN. Histologic analyses showed AIN 1 in 24 patients (22.2%), AIN 2 in 6 patients (5.6%), and AIN 3 in 10 patients (9.3%). In multivariable analyses, the use of HAART was associated with the absence of AIN (P 0.045). In MSM without HAART, HPV infection was detected significantly more often compared with those who used HAART (P 0.010). AIN was associated with HPV types 16 and 6. Conclusions: In this cross-sectional study in 250 HIV-positive