Clinical characteristics of 345 patients with coronavirus disease 2019 in Japan: A multicenter retrospective study.

Lu and colleagues recently reviewed mortality-related risk factors of COVID-19.1Lu L. Zhong W. Bian Z. Li Z. Zhang K. Liang B. et al.A comparison of mortality-related risk factors of COVID-19, SARS, and MERS: A systematic review and meta-analysis.J Infect. 2020; Abstract Full Text Full Text PDF Scopus (0) Google Scholar COVID-19 was first reported in Wuhan, China, in December 2019 and subsequently spread globally, leading to a pandemic;2Wiersinga W.J. Rhodes A. Cheng A.C. Peacock S.J. Prescott H.C. Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review.JAMA. 2020; Crossref Scopus (21) Google Scholar as of August 25, 2020, more than 23 million people worldwide had been confirmed to have COVID-19 infections, and more than 810,000 patients had died.3Johns Hopkins University and MedicineCOVID-19 map. Johns Hopkins Coronavirus Resource Centre, 2020https://coronavirus.jhu.edu/map.htmlGoogle Scholar Although approximately 80% of COVID-19 cases are classified as mild or asymptomatic, 15% of adults infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) developed severe illness and required oxygen supplementation, and an additional 5% progressed to a critical state.2Wiersinga W.J. Rhodes A. Cheng A.C. Peacock S.J. Prescott H.C. Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review.JAMA. 2020; Crossref Scopus (21) Google Scholar