Antibodies to the endoplasmic reticulum-resident chaperones calnexin, BiP and Grp94 in patients with rheumatoid arthritis and systemic lupus erythematosus

To investigate the presence of autoantibodies against mammalian heat shock proteins (Hsps) of the endoplasmic reticulum (ER) in patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis (Ssc) and inflammatory bowel disease (IBD). Sera from 40 healthy donors, 63 SLE patients, 22 Ssc patients, 14 patients with …