A new model of insulin-deficient diabetes: male NOD mice with a single copy of Ins1 and no Ins2

Naru Babaya,Maki Nakayama,Hiroaki Moriyama,R. Gianani,T. Still,Dongmei Miao,Liping Yu,John C. Hutton,George S. Eisenbarth

A new model of insulin-deficient diabetes: male NOD mice with a single copy of Ins1 and no Ins2

2006

Naru Babaya
Maki Nakayama
Hiroaki Moriyama
R. Gianani
T. Still
Dongmei Miao
Liping Yu
John C. Hutton
George S. Eisenbarth

Aims/hypothesis We describe a novel model of insulin-deficient diabetes with a single copy of the gene encoding insulin 1 (Ins1) and no gene encoding insulin 2 (Ins2).

Keywords:

Insulin
Insulin resistance
Knockout mouse
Endocrinology
Gene
Diabetes mellitus
NOD mice
Biology
Insulin tolerance test
Pancreatic hormone
Internal medicine
Genetically modified mouse

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