Clinical Diagnosis and Manifestation of Early Repolarization Syndrome

Although early repolarization has generally been considered benign for decades, there is increasing evidence that early repolarization is associated with an increased risk of ventricular fibrillation and sudden cardiac death. Early repolarization pattern in the inferior and/or lateral leads has recently been associated with increased risk of sudden cardiac death, and early repolarization syndrome has been proposed as a new entity of idiopathic ventricular fibrillation. Diagnostic criteria for early repolarization syndrome proposed in the expert consensus statement is available, but there are still some controversies about the diagnosis. Early repolarization syndrome shares clinical characteristics with Brugada syndrome, but the unique characteristics may be helpful for diagnosis and risk stratification.