Safety of Topical Methimazole for the Treatment of Melasma Transdermal Absorption, the Effect on Thyroid Function and Cutaneous Adverse Effects

Behrooz Kasraee,G.H. Safaee Ardekani,Amin Parhizgar,Farhad Handjani,Gholamhossein Ranjbar-Omrani,M. Samani,Mohammad Nikbakhsh,Nader Tanideh,A Eshraghian,Olivier Sorg,Jean-Hilaire Saurat

Safety of Topical Methimazole for the Treatment of Melasma Transdermal Absorption, the Effect on Thyroid Function and Cutaneous Adverse Effects

2008

Behrooz Kasraee
G.H. Safaee Ardekani
Amin Parhizgar
Farhad Handjani
Gholamhossein Ranjbar-Omrani
M. Samani
Mohammad Nikbakhsh
Nader Tanideh
A Eshraghian
Olivier Sorg
Jean-Hilaire Saurat

Methimazole is an oral antithyroid compound that exhibits a skin-depigmenting effect when used topically. However, the effect of topical methimazole on thyroid function has not been reported. This stu

Keywords:

Thyroid
Dermatology
Transdermal
Absorption (pharmacology)
Melasma
Side effect
Triiodothyronine
Oral administration
Adverse effect
Medicine
Internal medicine
Endocrinology
transdermal absorption
Methimazole
Thyroid hormones
thyroid function
Pharmacology
Pharmacokinetics

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