Primary genital lymphogranuloma venereum in the HIV pre-exposure prophylaxis era.

Lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) caused by Chlamydia trachomatis (CT) serovars L1-L3 (1) . In Europe, it is endemic among men who have sex with men (MSM) causing proctitis, mainly co-infected with HIV, since 2003 (2) . Its presentation as a genital lesion has been rarely described and accounts for around 5% of cases in the United Kingdom and France (3,4) . Increasing STIs rates in MSM have been reported during the last decade in several Western countries (5) , and it is plausible that HIV pre-exposure prophylaxis (PrEP) might contribute to maintaining this trend (6) . We report 2 cases with genital primary LGV mimicking primary syphilis seen at in our clinic in Barcelona.