ENCAPSULATING BEADS/CELLS IN UNIFORM-SIZED DROPLETS ON A MICROFLUIDIC CHIP UTILIZING HYDROPHILIC MODIFICATION OF A SURFACE

In this study we present a simple method to encapsulate beads or cells in the droplets on the microfluidic chip. The proposed chip integrates surface modification technique and pneumatic components, the droplets are formed directly without cross contamination of the carrier buffer. Therefore, the superfluous sample is recycled, which significantly reduces the sample consumption. Moreover, Beads and cells are encapsulated in a generated droplet and fixed in a defined area ready for assay and observation. Due to the advantages, this chip is promising to realize facile and reliable platform for biological and chemical applications.