Remitting seronegative symmetrical synovitis with pitting oedema syndrome-like symptoms associated with periodontitis: a case report

AbstractRemitting seronegative symmetrical synovitis with pitting oedema (RS3PE) is a rare inflammatory condition characterised by symmetrical synovitis of the hands and feet with pitting oedema. The etiology of RS3PE remains unclear. Although previous studies have reported associations between RS3PE and other diseases, none have described a possible association between RS3PE and periodontitis. The authors report a case of RS3PE syndrome-like symptoms improved by minocycline and oral care, including extraction of teeth.