Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT

RA Marsh, JW Leiding, BR Logan. J Clin Immunol . 2019;39(7):653–667 To evaluate the long-term effect of allogenic hematopoietic stem cell transplant (HCT) on chronic granulomatous disease (CGD)–associated inflammatory bowel disease (IBD) and assess the impact of IBD on transplant outcomes. A total of 145 patients with CGD who underwent allogenic HCT at 26 unique Primary Immune Deficiency Treatment Consortium (PIDTC) centers were included in this study. This was a retrospective study to evaluate clinical characteristics, laboratory findings, treatment and outcomes of patients with CGD who underwent allogenic HCT. CGD status was confirmed by …