Fine structure of Councilman bodies in the liver of Aluatta seniculus seniculus L. infected with yellow fever virus.

Abstract Councilman bodies found in hepatic cells of A.s. seniculus , naturally infected with yellow fever virus, are identified with the electron microscope. At the fine structure level, these bodies show no limiting membrane or internal vacuole membrane. The only constituents found are particles of different sizes presenting different osmium affinity. There are no lipid droplets or membranous components present within the bodies. No yellow fever virus particles are found in Councilman bodies; therefore, it can be concluded that their formation is not a direct consequence of the presence of viral particles.