Radiomic profiles via machine learning to predict response, overall survival, and KRAS status in metastatic colorectal tumors treated with FOLFOX/bevacizumab/hydroxychloroquine.

Saima Rathore,Mark H. O'Hara,Thomas Benjamin Karasic,Maryann Redlinger,Mark A. Rosen,Christos Davatzikos,Peter O'Dwyer

Radiomic profiles via machine learning to predict response, overall survival, and KRAS status in metastatic colorectal tumors treated with FOLFOX/bevacizumab/hydroxychloroquine.

2019

Saima Rathore
Mark H. O'Hara
Thomas Benjamin Karasic
Maryann Redlinger
Mark A. Rosen
Christos Davatzikos
Peter O'Dwyer

e15125Background: Autophagy is a resistance mechanism to chemotherapy that is inhibited by hydroxychloroquine (HCQ). We have reported a phase II trial of FOLFOX/bevacizumab/HCQ in 28 evaluable pati...

Keywords:

KRAS
FOLFOX
Hydroxychloroquine
Bevacizumab
Colorectal Tumors
Oncology
Pathology
Medicine
Internal medicine
overall survival
Chemotherapy

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