Validation of Tikhonov adaptively regularized gamma variate fitting with 24-h plasma clearance in cirrhotic patients with ascites

Carl A. Wesolowski,Lin Ling,Elias Xirouchakis,Maria Burniston,Richard C. Puetter,Paul Babyn,Ioannis G. Giamalis,Andrew K. Burroughs

Validation of Tikhonov adaptively regularized gamma variate fitting with 24-h plasma clearance in cirrhotic patients with ascites

2011

Carl A. Wesolowski
Lin Ling
Elias Xirouchakis
Maria Burniston
Richard C. Puetter
Paul Babyn
Ioannis G. Giamalis
Andrew K. Burroughs

Purpose The aim was to compare late-time extrapolation of plasma clearance (CL) from Tikhonov adaptively regularized gamma variate fitting (Tk-GV) and from mono-exponential (E1) fitting.

Keywords:

Medicine
Pathology
Renal function
Extrapolation
Tikhonov regularization
Radioisotope dilution technique
Random variate
Ascites
Liver function tests
Metabolic clearance rate
gamma variate
plasma clearance

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