Evaluation of Brucellosis in Patients and Diagnostic Tests

Brucellosis is a zoonotic bacterial disease which a gram negative bacterium called brucella creates it. Annually more than 500000 new cases are affected by this infection, So this disease is a remarkable threat for health. Because this infection has non-specific clinical symptoms such as fever, night sweet and these symptoms are similar to the other diseases, so detection of brucellosis is difficult. Blood culture is the gold standard. Now a day's some kinds of tests like serological tests such as SAT, 2ME, RBT and coombs test which are approved. Some tests like ELISA for its screening trait is adjustable. More ever, LFA as a kind of this test could be beneficial in diagnosis of infection. PCR is a molecular diagnostic test which is more prevalent than other common tests, according to sensitivity and specificity. In this note we will evaluate these methods.