Inhibition of Hormone and Cytokine-stimulated Osteoclastogenesis and Bone Resorption by Interleukin-4 and Interleukin-13 Is Associated with Increased Osteoprotegerin and Decreased RANKL and RANK in a STAT6-dependent Pathway

Py Palmqvist,Pernilla Lundberg,Emma Persson,Anders Johansson,Inger Lundgren,Anita Lie,H. Herschel Conaway,Ulf H. Lerner

Inhibition of Hormone and Cytokine-stimulated Osteoclastogenesis and Bone Resorption by Interleukin-4 and Interleukin-13 Is Associated with Increased Osteoprotegerin and Decreased RANKL and RANK in a STAT6-dependent Pathway

2006

Py Palmqvist
Pernilla Lundberg
Emma Persson
Anders Johansson
Inger Lundgren
Anita Lie
H. Herschel Conaway
Ulf H. Lerner

Interleukin (IL)-4 and IL-13 are cytokines that inhibit bone resorption. Data showing an inhibitory effect of IL-4 and IL-13 on RANK mRNA in mouse calvariae were first reported at the 22nd American ...

Keywords:

Interleukin 4
Hormone
Interleukin 13
Osteoprotegerin
Interleukin
Bone resorption
RANKL
Molecular biology
Cytokine
Endocrinology
Internal medicine
Biology
STAT6

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