Risk Factors for Mortality among Patients with Sepsis Complicated with Active Tuberculosis

OBJECTIVES: To determine risk factors associated with mortality of patients with sepsis complicated with active tuberculosis (TB) in intensive care units (ICU). METHODS: We reviewed medical records of 61 TB patients whom were admitted to the ICU in West China Hospital of Sichuan University, among whom 19 were dead. Logistic regression models were established to determine predictors of mortality. RESULTS: The acute physiology and chronic health evaluation (APACHE Ⅱ) score, smear-positive sputum, delayed treatment of active TB and acute kidney dysfunction were independent predictors of mortality. CONCLUSIONS: Mortality of patients with sepsis complicated with active tuberculosis is high. APACHE Ⅱ score, smear-positive sputum, delayed treatment of active TB and acute kidney dysfunction are independent predictors of mortality.