SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection.
2019
Introduction
Mammography is the gold standard for early breast cancer detection, but shows important limitations. Blood-based approaches on basis of cell-free DNA (cfDNA) provide minimally invasive screening tools to characterize epigenetic alterations of tumor suppressor genes and could serve as a liquid biopsy, complementing mammography.
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