To study the correlation between carrier status of nasal Staphylococcus aureus in patients on haemodialysis with hepatitis C, hepatitis B and their sociodemographic features

AIM: To study the correlation of nasal Staphylococcus aureus carrier status in patients on haemodialysis, infected by hepatitis C virus (HCV), hepatitis B virus (HBV), and their sociodemographic features. SUBJECTS AND METHODS: A survey, including patients ' sociodemographic features, was applied to patients by physicians in face to face interviews. Medical records regarding their serologic data were recorded from haemodialysis centres. Nasal swab samples of 2 cm depth from both nostrils of patients were obtained for nasal culture. Samples were inoculated in 5% sheep blood agar and incubated in an incubator at a temperature of 37ÂoCfor 24 hours. The results were studied by the same microbiologist. RESULTS: A total of 185 patients were enrolled in the study. According to culture results, 14.1% of patients (n = 26) had methicillin sensitive Staphylococcus aureus (MSSA) and 1.1% (n = 2) had methicillin resistant Staphylococcus aureus (MRSA). Status of viral hepatitis was 3.8% (n = 8), 10.8% (n = 20) for HBV and HCV, respectively. Forty per cent (n = 8) of patients with HBV (+) had MSSA carrier status. Statistically significant positive correlation between MSSA and HCV carrier was detected (r = 0.325, p = 0.001) but not between HBV carrier and MSSA (p = 0.255). CONCLUSION: In the present study, significant positivity was detected between MSSA carrier status and HCV in patients on haemodialysis and who have lived together with OBJETIVO: Estudiar la correlaciA³n entre el portador del Estafilococo dorado (Staphylococcus aureus) nasal en pacientes de hemodiAilisis infectados por el virus de la hepatitis C (VHC), el virus de la hepatitis B (VHB), y sus caracterA­sticas sociodemogrAificas. SUJETOS Y MA‰TODOS: Una encuesta que incluA­a caracterA­sticas sociodemogrAificas de los pacientes fue aplicada a pacientes por mA©dicos en entrevistas cara a cara. Historias clA­nicas contentivas de sus datos serolA³gicos, fueron registradas a partir de los centros de hemodiAilisis. Muestras defrotis nasales de 2 cm de profundidad de ambas fosas nasales, fueron obtenidas para un cultivo nasal. Se inocularon muestras en agar de sangre de oveja al 5%, e incubadas en una incubadora a una temperatura de 37ÂoC por 24 horas. Los resultados fueron examinados por el mismo microbiA³logo. RESULTADOS: Un total de 185 pacientes fueron enrolados en el estudio. SegAon los resultados del cultivo, 14.1% pacientes (n = 26) tenA­an estafilococo dorado sensible a la meticilina (MSSA) y 1.1% (n = 2) tenA­an estafilococo dorado resistente a la meticilina (MRSA). El estatus de las hepatitis virales fue 3.8% (n = 8), y 10.8% (n = 20) para HVB y HVC respectivamente. Cuarentapor ciento (n = 8) de los pacientes con HVB (+) eran portadores del MSSA. EstadA­sticamente, se detectA³ una correlaciA³n positiva significativa (r = 0.325, p = 0.001), entre MSSA y el portador de VHC, no asA­ entre el portador del VHByMSSA (p = 0.255). CONCLUSIA“N: En el estudio presente, se detectA³ una positividad significativa entre el estatus de; portador de MSSA y los pacientes de VHC en hemodiAilisis, que vivA­an junto con [= dos o menos de dos] miembros de la familia en casa. En particular, se observA³ una correlaciA³n estadA­sticamente significativa entre HCV (+) y el portador MSSA.(AU)