Application progress of botulinum toxin type A in the nervous system diseases

In recent years,with the deepening study on the mechanism of botulinum toxin type A,the range of its applications in the nervous system diseases continues to expand.Because botulinum toxin type A produces partial chemical denervation of the muscle resulting in a localized reduction in muscle activity,it can be used to treat hemifacial spasm,idiopathic blepharospasm,oromandibular dystonia,spasmodic torticollis,tic disorder,limb spasticity after stroke and spastic cerebral palsy.In addition,it has recently begun to show some benefit in the control of hyperhidrosis ang excessive salivation disease on account of its effects of the autonomic nervous system.It may also prove useful in treatment of a variety of headache and neuralgia owing to its analgesic effects.Therefore,botulinum toxin type A has become an important treatment option in the field of neurology.