Cancer cell-oriented migration of mesenchymal stem cells engineered with an anticancer gene ( PTEN ): an imaging demonstration

Background Mesenchymal stem cells (MSCs) have been considered to hold great potential as ideal carriers for the delivery of anticancer agents since the discovery of their tumor tropism. This study was performed to demonstrate the effects of phosphatase and tensin homolog (PTEN) engineering on MSCs’ capacity for cancer cell-oriented migration.