Mechanism and Effect of Esculetin in an Experimental Animal Model of Inflammatory Bowel Disease

Aline Witaicenis,Ana Carolina Luchini,Clélia Akiko Hiruma Lima,Sérgio Luis Felisbino,Luis A. Justulin,Natividad Garrido-Mesa,Pilar Utrilla,Julio Gálvez,L. C. Di Stasi

Mechanism and Effect of Esculetin in an Experimental Animal Model of Inflammatory Bowel Disease

2013

Aline Witaicenis
Ana Carolina Luchini
Clélia Akiko Hiruma Lima
Sérgio Luis Felisbino
Luis A. Justulin
Natividad Garrido-Mesa
Pilar Utrilla
Julio Gálvez
L. C. Di Stasi

Esculetin is a coumarin derivative with high antioxidant activity. In a rat experimental model of inflammatory bowel disease induced by trinitrobenzenesulfonic acid, esculetin at the dose of 5mg/Kg...

Keywords:

Prednisolone
Interleukin-1beta
Myeloperoxidase
Immunology
Colitis
Tumor necrosis factor alpha
Reactive Oxygen Metabolite
Animal model
Inflammatory bowel disease
Medicine
experimental animal
drug effect

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