Short physical performance battery discriminates clinical outcomes in hospitalized patients aged 75 years and over.

Abstract Aim Low physical function is associated with poor outcomes in hospitalized patients; however, little is known about vulnerable populations such as those aged ≥75 years. We examined whether the Short Physical Performance Battery (SPPB) was associated with clinical outcomes in hospitalized patients aged ≥75 years. Methods In total, 147 patients aged ≥75 years (mean age, 86.5 ± 4.7 years; 89 males) completed the SPPB and Mini-Mental State Examination (MMSE) before hospital discharge. Patients were divided into three groups by SPPB score: 0 (unable to perform SPPB), 1–6 (low performance), and 7–12 (high performance). The first occurrence of all-cause unplanned readmission or all-cause mortality within 1 year after discharge was set as the endpoint. Results The median SPPB score of the study population was 2; 41% were unable to perform SPPB, 33% had low performance, and 26% had high performance. High SPPB was associated with younger age, higher BMI, and higher MMSE score. During the follow-up period, 35 (23.8%) patients were readmitted to hospital and 19 (12.9%) died. Even after adjusting for covariates, SPPB score was a significant and independent predictor of poor outcomes (hazard ratio for 1 point increase in SPPB, 0.88; P = .002). The subgroup analysis showed SPPB was inversely associated with the occurrence of poor outcomes in patients with cognitive impairment. Conclusions SPPB is inversely associated with risks for readmission and mortality in hospitalized patients aged ≥75 years, especially those with cognitive impairment. The present results indicate the SPPB is useful for accurate prognosis in hospital settings.