A case of pyostomatitis vegetans associated with ulcerative colitis

A case of pyostomatitis vegetans associated with ulcerative colitis is reported. A 57-year-old man with a history of ulcerative colitis was referred to our hospital because of pain in both sides of the buccal mucosa and malnutrition. A snail-track-shaped ulcer and miliary pustules with a cobblestone appearance were found in both sides of the buccal mucosa and soft palate. Treatment with topical corticosteroids had no effect on this lesion. The presence of abdominal pain and hematochezia led us to suspect a recurrence of ulcerative colitis. Immediately after the systemic administration of corticosteroids was started, the oral mucosal lesions resolved. This case suggests that treatment of ulcerative colitis with systemic corticosteroids is required to cure pyostomatitis vegetans.