Synthesis, DNA-binding, and antitumor activity of polypyridyl-ruthenium(II) complexes [Ru(L)2(DClPIP)] (L = bpy, phen; DClPIP = 2-(2,4-dichlorophenyl)-1H-imidazo[4,5-f][1, 10]phenanthroline)

Shouhai Guan,Tao Pan,Yanyang Zhang,Zhaolin Zeng,Luwen Mu,Duo Zhu,Boyang Chang,Kangdi Zheng,Jiesheng Qian,Qiang Xie,Wenjie Mei,Wenjie Tang,Mingjun Bai

Synthesis, DNA-binding, and antitumor activity of polypyridyl-ruthenium(II) complexes [Ru(L)2(DClPIP)] (L = bpy, phen; DClPIP = 2-(2,4-dichlorophenyl)-1H-imidazo[4,5-f][1, 10]phenanthroline)

2019

Shouhai Guan
Tao Pan
Yanyang Zhang
Zhaolin Zeng
Luwen Mu
Duo Zhu
Boyang Chang
Kangdi Zheng
Jiesheng Qian
Qiang Xie
Wenjie Mei
Wenjie Tang
Mingjun Bai

AbstractTwo new ruthenium(II) complexes, [Ru(bpy)2(DClPIP)](ClO4)2 (1) and [Ru(phen)2(DClPIP)](ClO4)2 (2) (bpy = 2,2′-bipyridine, phen = 1,10-phenanthroline, and DClPIP = 2-(2,4-dichlorophenyl)-1H-...

Keywords:

Ruthenium
Medicinal chemistry
Synthesis dna
Luminescence
Titration
Photochemistry
MTT assay
A549 cell
Circular dichroism
Phenanthroline
Chemistry
antitumor activity

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