A split mouth clinical study to compare Subepithelial connective tissue graft and Guided tissue regeneration in the treatment of Miller’s class I and II gingival recession.

2021 
ABSTRACT Background: Gingival recession (GR) can result in hypersensitivity, esthetic concern to the patient, and chances for root caries. The purpose of this randomized clinical study was to evaluate the effect of guided tissue regeneration (GTR) procedure using a bioabsorbable collagen membrane in comparison to autogenous Subepithelial connective tissue graft (SCTG) for root coverage in Miller’s class I and II gingival recession defects. Materials and methods: In this split mouth study, 10 patients with 20 contralateral Miller’s class I or II recession defects were randomly treated with coronally advanced flap using either Subepithelial connective tissue graft (control group)  or resorbable collagen membrane (experimental group). The clinical evaluations were done using plaque index, gingival index, height of gingival recession, probing sulcus depth and clinical attachment level at baseline, 3 and 6 months post- operatively. Results: Data analysis was done using descriptive statistics and student’s t test was used for comparisons. P value <0.01 was considered to be significant. Both the groups showed complete resolution of the defects at 6 months post operatively. Inter group comparison between both the groups at 6 months showed no statistically significant differences in any of the clinical parameters. Conclusion:  Predictable outcome were observed in both the groups and indicated that collagen based guided tissue regeneration membrane i.e. ProGide can be safely used.
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