Patients with Idiopathic Pulmonary Nontuberculous Mycobacterial Disease Have Normal Th1/Th2 Cytokine Responses but Diminished Th17 Cytokine and Enhanced Granulocyte-Macrophage Colony-Stimulating Factor Production

Un-In Wu,Kenneth N. Olivier,Douglas B. Kuhns,Danielle L. Fink,Elizabeth P. Sampaio,Adrian M. Zelazny,Shamira J. Shallom,Beatriz E. Marciano,Michail S. Lionakis,Steven M. Holland

Patients with Idiopathic Pulmonary Nontuberculous Mycobacterial Disease Have Normal Th1/Th2 Cytokine Responses but Diminished Th17 Cytokine and Enhanced Granulocyte-Macrophage Colony-Stimulating Factor Production

2019

Un-In Wu
Kenneth N. Olivier
Douglas B. Kuhns
Danielle L. Fink
Elizabeth P. Sampaio
Adrian M. Zelazny
Shamira J. Shallom
Beatriz E. Marciano
Michail S. Lionakis
Steven M. Holland

Objective Although disseminated nontuberculous mycobacterial infection is attributed to defects in the interleukin (IL)-12/interferon-γ circuit, the immunophenotype of idiopathic pulmonary nontuberculous mycobacterial (PNTM) disease is not well defined.

Keywords:

Cytokine
Immunology
Disease
Granulocyte macrophage colony-stimulating factor
Virology
Medicine
Interleukin 12
Monocyte
Nontuberculous mycobacteria
Antigen
Interleukin
Mycobacterium abscessus

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