Radiofrequency-Hyperthermia in Combination with Chemo and Radiotherapy in Palliative Treatment of Breast Cancer: A Case Report

In March 1999, a 35 yr. old female patient presented with a palpable mass in the left breast and positive axillary lymph nodes. Invasive ductal carcinoma (IDC) was diagnosed after core cut biopsy. Receptors were negative and a skin probe was free of malignant infiltration. Preoperative chemotherapy (PCT) was given and because of complete remission breast-conserving therapy performed in May. The specimen showed a small residual tumor of IDC only. Under continued PCT a local relapse appeared on the same side within one month postoperatively. A triple therapy consisting of PCT, Radiofrequency-Hyperthermia (RF-HT) and Radiotherapy (RTX) was given when by end of August 1999 the area of the local malignant inflammation has exceeded 100 cm2. The recurrent disease completely disappeared. RF-HT in combination with PCT and RTX seems to be an excellent tool in patients with recurrent breast cancer.