Odontogenic myxoma containing osteocement-like tissue: Report of a case with an unusual histopathological feature

Abstract An odontogenic myxoma occurring in the mandible of a 54-year-old Japanese male is described; this contained unusual osteocement-like spherules, which are rarely reported. The radiological examination revealed a multilocular lesion with mixed radiolucent–radiopaque content. We performed a segmental mandibulectomy, and reconstructed the mandible using a titanium plate and iliac bone. Histopathologically, the tumor was composed mainly of myxomatous stroma in which a few stellate and spindle-shaped cells were suspended. A few odontogenic epithelial nests were also observed. In addition, there were osteocement-like spherules, showing concentric lamination. The presence of these osteocement-like structures has only been reported in three previous cases.