Novel Approach for Clinical Validation of the cobas KRAS Mutation Test in Advanced Colorectal Cancer

Abha Sharma,Guili Zhang,Shagufta Aslam,Karen Yu,Melody Chee,John F. Palma

Novel Approach for Clinical Validation of the cobas KRAS Mutation Test in Advanced Colorectal Cancer

2016

Abha Sharma
Guili Zhang
Shagufta Aslam
Karen Yu
Melody Chee
John F. Palma

Aim Our objective was to assess the performance of the cobas test versus comparators for KRAS mutation status and predicting clinical response to anti-epidermal growth factor receptor (EGFR) therapy in patients with metastatic colorectal cancer (mCRC).

Keywords:

Cetuximab
Pathology
Sanger sequencing
KRAS
Colorectal cancer
DNA Mutational Analysis
Oncology
Growth factor receptor
Mutation
Medicine
Internal medicine
advanced colorectal cancer
neoplasm staging
kras mutation
in patient
treatment outcome

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations