Sulfonated-titanomagnetite nanoparticles as potential and recyclable catalyst for the synthesis of dihydroquinazoline and hexahydroquinoline derivatives under solvent free condition

2020 
The performance of sulfonated-titanomagnetite nanoparticles (Fe3-xTixO4-SO3H NPs) as useful and recyclable nanocatalyst for the synthesis of dihydroquinazoline and hexahydroquinoline derivatives through multi-component reaction approach in solvent-free condition were investigated extensively. The successful synthesis of mentioned derivatives were confirmed using Fourier-transform infrared (FTIR) as well as 1H/13C nuclear magnetic resonance (NMR) spectroscopies. According to the results, the employed nanocatalyst have some advantages such as high catalytic activity in short reaction time, good-to-excellent isolated yields in most cases, easy work up process, smooth processing feature of the reactions, facile recovery using an external magnetic field, and re-usability for four times without significant loss in its activity.
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