Cyclophosphamide Creates a Receptive Microenvironment for Prostate Cancer Skeletal Metastasis

Serk In Park,Jinhui Liao,Janice E. Berry,Xin Li,Amy J. Koh,Megan E. Michalski,Matthew R. Eber,Fabiana N. Soki,David Sadler,Ha Sud,Sandra Tisdelle,Stephanie Daignault,Jeffrey A. Nemeth,Linda A. Snyder,Thomas J. Wronski,Kenneth J. Pienta,Laurie K. McCauley

Cyclophosphamide Creates a Receptive Microenvironment for Prostate Cancer Skeletal Metastasis

2012

Serk In Park
Jinhui Liao
Janice E. Berry
Xin Li
Amy J. Koh
Megan E. Michalski
Matthew R. Eber
Fabiana N. Soki
David Sadler
Ha Sud
Sandra Tisdelle
Stephanie Daignault
Jeffrey A. Nemeth
Linda A. Snyder
Thomas J. Wronski
Kenneth J. Pienta
Laurie K. McCauley

The chemotherapeutic drug cyclophosphamide, used in the treatment of many kinds of cancer, is found unexpectedly to exert a prometastatic effect within bone.

Keywords:

Neoplasm Transplantation
Bone marrow
Drug
Cancer
Prostate cancer
Interleukin 6
Metastasis
Immunology
Cyclophosphamide
Internal medicine
Medicine
Oncology
myeloid cells
chemotherapeutic drugs
skeletal metastasis

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