COVID-Toes or Pernio?

Abstract “COVID toes” are a new phenomenon of pernio-like lesions that has been associated with COVID-19 infection. As dermatology practices reopen and increase patient volumes amidst the waning of the coronavirus pandemic, it is important to consider the finding of pernio and pernio-like lesions in the context of both COVID-19 and its other possible etiologies. This article will discuss possible causes of pernio and pernio-like lesions and offer suggestions for appropriate diagnostic work-up and management when indicated.