Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer.

Jia Yang,Aydin Eresen,Junjie Shangguan,Quanhong Ma,Vahid Yaghmai,Zhuoli Zhang

Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer.

2021

Jia Yang
Aydin Eresen
Junjie Shangguan
Quanhong Ma
Vahid Yaghmai
Zhuoli Zhang

Pancreatic ductal adenocarcinoma (PDAC) is associated with highly immunosuppressive tumor microenvironment (TME) that can limit the efficacy of dendritic cell (DC) vaccine immunotherapy. Irreversib...

Keywords:

Tumor microenvironment
Pancreatic cancer
Immunosuppression
Cancer research
Irreversible electroporation
Magnetic resonance imaging
Ablation
Immunotherapy
Dendritic cell
Medicine

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