MP09-09 THE ASSOCIATION BETWEEN PATHOLOGIC FEATURES OF LYMPH NODE METASTASIS IDENTIFIED AFTER PROSTATECTOMY AND THE RISK OF BIOCHEMICAL RECURRENCE: A STUDY OF 280 CASES

2019 
INTRODUCTION AND OBJECTIVES:To determine the association between the number of positive lymph nodes (LN), extranodal extension (ENE), size and Grade Group (GG) of metastatic focus (MET) in in the LN and risk of biochemical recurrence after prostatectomy in patients with prostate cancer (Pca).METHODS:We evaluated biochemical recurrence (BCR) in 280 node positive cases who underwent radical prostatectomy (RP) between 2006-2018 at our institution. Cases with prior treatment and known metastasis at the time of surgery were excluded. Parameters recorded included number & size of positive LN. Size & GG of largest MET & ENE were also noted.RESULTS:Average follow up period was 13.4 months. The Average number of LN retrieved was 14.7 with an average of 2 positive LN per case. ENE was identified in 99/244 (41%).Size of the largest positive LN was 10 mm or less in 71% of the cases and the size of the largest MET was < 2 mm (micrometastasis) in 107/261 cases (41%). A solitary LN positive was found in 166/280 (59%) of...
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