Frecuencia de síndrome metabólico en pacientes con hidradenitis supurativa en institución Argentina

espanolIntroduccion: La hidradenitis supurativa es una enfermedad autoinflamatoria cronica, cuya fisiopatogenia puede tener relacion con el sindrome metabolico. Objetivo: Comparar la frecuencia de sindrome metabolico en pacientes con hidradenitis supurativa en relacion con un grupo control. Material y metodos: Estudio observacional, retrospectivo y analitico con diseno muestral no probabilistico. Se analizaron casos de pacientes con hidradenitis supurativa y controles seleccionados al azar, apareados por edad y sexo. Se analizaron las variables: estadio de Hurley, calidad de vida, sexo, edad, peso, altura, indice de masa corporal (IMC) y los componentes del sindrome metabolico segun el Adult Treatment Panel III. Resultados: Se estudiaron 22 casos y 44 controles. Los pacientes con hidradenitis supurativa fueron en su mayoria mujeres (72.7%), entre 31 y 40 anos (31.8%) con estadio Hurley I (54.6%) con afectacion leve de la calidad de vida (54.6%), obesos (63.7%), con perimetro abdominal aumentado (86.4%) y HDL inferior al sugerido por el ATP III (59.1%). Dos pacientes (9.1%) tuvieron hipertension arterial y cinco (22.7%) cumplieron los criterios para sindrome metabolico. La presencia de obesidad fue mas frecuente entre los casos (OR 2.82 IC 1.50-5.27 p = 0.006), con mayor frecuencia de perimetro abdominal aumentado (OR 5.78 IC 1.49-22.39 p = 0.007) y HDL disminuido (p = 0.06 OR 3.10 IC 1.07-8.94). Conclusion: En la poblacion estudiada no se pudo probar mayor prevalencia de sindrome metabolico, pero se observo relacion directa con obesidad (IMC y perimetro abdominal aumentado). EnglishIntroduction: Hidradenitis suppurativa (HS) is a chronic autoinflammatory disease, whose physiopathogenesis may be related to the metabolic syndrome (MS). Objective: To compare the frequency of metabolic syndrome in patients with hidradenitis suppurativa in relation to a control group. Material and methods: Observational, retrospective and analytical study with non-probabilistic sample design. We analyzed cases of patients with hidradenitis suppurativa and randomly selected controls, matched by age and sex. The following variables were studied: Hurley stage, quality of life, sex, age, weight, height, body mass index (BMI) and the components of metabolic syndrome according to the Adult Treatment Panel III. Results: 22 cases and 44 controls were studied. Patients with hidradenitis suppurativa were mostly women (72.7%), between 31 and 40 years (31.8%), Hurley stage I (54.6%) with mild impairment of quality of life (54.6%), obese (63.7%), with increased abdominal perimeter (86.4%) and lower HDL than suggested by ATP III (59.1%). Two patients (9.1%) had arterial hypertension and five (22.7%) met the criteria for metabolic syndrome. The presence of obesity was more frequent amongnst cases (OR 2.82 IC 1.50-5.27 p = 0.006), with greater frequency of increased abdominal circumference (OR 5.78 IC 1.49-22.39 p = 0.007) and decreased HDL (p = 0.06 OR 3.10 IC 1.07-8.94). Conclusion: In the studied population it was not possible to prove a higher prevalence of metabolic syndrome, but a direct relationship was observed with obesity (BMI and increased abdominal perimeter).