Screening trial of cancer chemopreventive agent by using combination of DNA chip technology and Cell Signaling Network DataBase (CSNDB)

Mechanism of the cancer prevention was complicated, and the elucidation was difficult if it was a conventional experiment system. We are building the system which put the latest technology to reach a screening trial of cancer preventive agents from an approach to find candidate cell signaling pathway of cancer prevention by using combination of DNA chip technology and Cell Signaling Network Database (CSNDB) maintained by the National Institute of Health Sciences. As for these strategies, we think that it is an interesting trial when we examine the effectiveness from an interesting pathway search in investigation for an unknown cancer preventive agent. We are in the way, but demonstrate a part of our study and try to think about the future prospects.