Phase I/Ib study of pembrolizumab and vorinostat in patients with metastatic NSCLC (mNSCLC): Updated results.

Andreas Saltos,Tawee Tanvetyanon,Eric B. Haura,Ben C. Creelan,Scott Antonia,Michael Rahman Shafique,Hong Zheng,Wenjie Dai,Zhihua Chen,James J. Saller,Nishan Tchekmedyian,Kristen Goas,Ram Thapa,Theresa A. Boyle,Dung-Tsa Chen,Amer A. Beg,Jhanelle E. Gray

Phase I/Ib study of pembrolizumab and vorinostat in patients with metastatic NSCLC (mNSCLC): Updated results.

2019

Andreas Saltos
Tawee Tanvetyanon
Eric B. Haura
Ben C. Creelan
Scott Antonia
Michael Rahman Shafique
Hong Zheng
Wenjie Dai
Zhihua Chen
James J. Saller
Nishan Tchekmedyian
Kristen Goas
Ram Thapa
Theresa A. Boyle
Dung-Tsa Chen
Amer A. Beg
Jhanelle E. Gray

9073Background: Histone deacetylase inhibitors (HDACi) enhance tumor immunogenicity through several mechanisms and may augment response to immune checkpoint inhibitors (ICI). We report updated resu...

Keywords:

Pathology
Vorinostat
Cancer research
Pembrolizumab
Immunogenicity
Immune checkpoint
Histone deacetylase
Medicine
immune checkpoint inhibitors
in patient

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