A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery

Abstract A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) had fever and headache, and thus was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and brain abscess. The endoscopic endonasal surgery was performed at this point, providing drainage for the rhinosinusitis and abscess. Histopathological findings showed the mucormycosis.