Acid-base management during hypothermic circulatory arrest for cardiac surgery

Four fundamental strategies for acid-base management during hypothermic cardio-pulmonary by-pass (H-CPBP) are pH-stat, \({P_{c{o_2}}}\) -stat, alpha-stat, and respiratory alkalosis. For H-CPBP in man, the blood is diluted with saline solution to HCT 20%(s is about 20 slykes). On the logC-T graph pH and \({P_{c{o_2}}}\) lines are both horizontal. This graph closely approximates the human situation.