Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway
2015
DNA double-strand breaks (DSBs), a highly deleterious form of DNA damage, are associated with multiple types of broken ends. Here, the authors identify a XRCC4-like factor that functions in the non-homologous end-joining DNA repair pathway to repair DSBs with complex broken ends.
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