An Ontology-Based Personalized Decision Support System for Use in the Complex Chronically Ill Patient.

: Management of the complex chronically ill patient is highly problematic. This is due to the need to complement recommendations in clinical guidelines with recommendations based on treatments performed on a representative set of patients. It is necessary to identify conflicts between the recommendations of different guidelines designed for handling specific chronic diseases. The PITeS-TIiSS project (code PI15/01213) aims to overcome this problem by designing and deploying an ontology-based personalized clinical decision support tool. This helps to improve personalized decisions and reduces variability in clinical practice in an integrated care environment. This paper describes the methodology followed in developing the ontology used to infer clinical knowledge and to develop and implement the support tool. The tool will access the information provided by the Electronic Health Record of Andalusian Health Public Service, the main healthcare provider in a region in Spain with more than eight million inhabitants.