Vortex grinding for mechanochemistry: application for automated supramolecular catalysis and preparation of a metal–organic framework

An automated grinding method based on a vortex mixer has been developed. The method enables simultaneous grinding and UV-irradiation, as well as in situ monitoring of solid-state reactivity. The method has been applied to a cocrystallization, supramolecular catalysis, and the preparation of a metal–organic framework.