Antithrombin activity and heparin response in neonates and infants undergoing congenital cardiac surgery: a retrospective cohort study
2016
Purpose
The immature coagulation system during infancy has age-related physiological differences in proteins that contribute to significant variation in heparin responsiveness through alterations in heparin-enhanced thrombin inhibition. The primary aim of this study was to evaluate the relationship between preoperative antithrombin (AT) activity and heparin responsiveness in neonates and infants undergoing congenital cardiac surgery.
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