LIQUIBAND SURGICAL TISSUE ADHESIVE COMPARED TO CONVENTIONAL WOUND MANAGEMENT

Liquiband is a new tissue adhesive: It works like super glue – it is attached to the wound edges, it sets within seconds and lasts for about two weeks. The glue then flakes off automatically as the skin regenerates. There is no need for suture removal. A second step forms a waterproof layer over the wound. We compared in a prospective randomized trial the Liquiband glue to skin staples. Over a 9 month period (May 2005 to January 2006) we enrolled a total of 80 patients, 40 in each group. The patients were booked for elective limb surgery and agreed to participate in the study. The surgical wounds were closed in layers. The skin was then either closed with Liquiband or skin staples. A follow up was a weeks 2, 6 and 18. The wound healing was photographically documented. The wounds were assessed according to the Hollander wound scoring system and a patient satisfaction score. Ethical approval was obtained. The two groups were matched for sex, age, body-mass index and smoking. There was a similar total wound length in both groups. All wounds healed. In the Liquiband group 4 superficial infections occurred, one dehiscence due to glue removal by the patient. In the skin staples group we had 6 superficial infections. The patient satisfaction score was lower in the skin staple group (7.0 compared to 8.3 in the Liquiband group) and on the Hollander wound scoring system there were 10% more step-off borders and 12% more edge inversions in the skin staple group. The glue did not stain the skin or leave visible marks. The authors conclude that the Liquiband skin glue is safe and effective for elective surgery. The Liquiband skin glue does not require staple removal after wound healing and the waterproof closure of the wound provides additional safety.