Protective Effect of Tonapofylline (BG9928), an Adenosine A1 Receptor Antagonist, against Cisplatin-Induced Acute Kidney Injury in Rats

Alan Gill,Kathleen Wortham,Don Costa,Wendell Davis,Barry Ticho,Eric Whalley

Protective Effect of Tonapofylline (BG9928), an Adenosine A1 Receptor Antagonist, against Cisplatin-Induced Acute Kidney Injury in Rats

2009

Alan Gill
Kathleen Wortham
Don Costa
Wendell Davis
Barry Ticho
Eric Whalley

Background/Aims: Cisplatin (CIS) induces nephrotoxicity partly through renal vasoconstriction and decreased glomerular filtration effects thought to involve adenosine acting on aden

Keywords:

Renal function
Antagonist
Acute kidney injury
Adenosine
Adenosine receptor
Adenosine A1 receptor
Vasoconstriction
Endocrinology
Nephrotoxicity
Internal medicine
Medicine

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