Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy

H. Diego Folco,Venkata R. Chalamcharla,Tomoyasu Sugiyama,Gobi Thillainadesan,Martin Zofall,Vanivilasini Balachandran,Jothy Dhakshnamoorthy,Takeshi Mizuguchi,Shiv I. S. Grewal

Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy

2017

H. Diego Folco
Venkata R. Chalamcharla
Tomoyasu Sugiyama
Gobi Thillainadesan
Martin Zofall
Vanivilasini Balachandran
Jothy Dhakshnamoorthy
Takeshi Mizuguchi
Shiv I. S. Grewal

Uniparental disomy in fission yeast is triggered by aberrant expression of gametogenic genes in vegetative cells, and is associated with the activation of meiotic cohesin Rec8 in cells with defects in the RNA interference machinery.

Keywords:

Meiosis
Heterochromatin
Chromosome segregation
Gene
Genetics
RNA interference
Chromosome
Uniparental disomy
Cohesin
Biology
Homologous chromosome
Centromere
Heterochromatin assembly

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