Surgical resection for liver metastases developing 10 and 21 years after primary surgery for mucinous colon adenocarcinoma: A Case Report

Abstract Introduction Optimal management for liver metastases from colorectal mucinous adenocarcinoma is still controversial. Here, we report such a case of liver metastases which developed twice with 10 year intervals after curative resection. Case presentation An 84-year-old man had undergone a radical left hemicolectomy for descending colon cancer at 63 years of age. The histopathological diagnosis was mucinous adenocarcinoma. Ten years later, he was found to have a cystic tumor in liver and underwent partial hepatectomy of segment 5. Moreover, eleven years later of hepatic resection, CT showed low density tumor with calcification in remnant liver and partial hepatectomy of segment 8 was performed. Histopathological and immunohistochemical findings of each liver tumor indicated metastasis from primary colon mucinous adenocarcinoma. It is rare that colorectal mucinous adenocarcinoma recurs twice after long intervals of 10 years. However, also in a patient with a history of colorectal mucinous adenocarci...